The recruitment of families for the TRIGR study spanned over four and a half years and was completed
in February 2007.
For the study to be successful, we hope that all the children will continue in the study and be a part of the TRIGR family until the youngest child reaches the age of 10 years
in 2017. The oldest participants will then be 14 years old.
Altogether, 2159 children from 15 countries were included in the study
Milestone: RECRUITMENT IS COMPLETED. NO MORE BABIES WILL BE ENROLLED.
Journal of the American Medical Association (JAMA) (2 Jan 2018),
article by Writing Group for the TRIGR Study Group
Outcome of study endpoint: effect of weaning to an extensively hydrolyzed casein infant formula, versus a regular cow's
milk-based infant formula, on the incidence of type 1 diabetes in children with a genetic risk for type 1 diabetes.
For link to abstract of journal article, click here (then scroll
to "Trial End" section).
Journal of the American Medical Association (JAMA) (11 June 2014),
article by M. Knip et al. for the TRIGR Study Group
Outcome of first study endpoint: positivity for at least two diabetes-associated autoantibodies by the age of 6 years.
For link to journal article, click here (then scroll to "History" section).
New England Journal of Medicine (11 November 2011),
article by M. Knip et al.
Finnish pilot study shows that infant feeding plays role in initiation of T1D in children carrying increased genetic risk for the disease.
Download Publications List [pdf]
TRIGR FAMILY NEWS (newsletters)
HONORARY DOCTOR AWARD TO PROF. JEFFREY KRISCHER
Dec 19, 2017: Lund University in Sweden has announced that Jeffrey Krischer, PhD, Principal Investigator of TRIGR's Data Management Unit,
will be awarded an Honorary Doctor of Medicine at a ceremony in Lund in May 2018. Dr. Krischer is being recognized for his contributions to research into mechanisms
behind autoimmune diseases including diabetes and celiac disease. He has been involved with the TRIGR Study since 2002. He also is Director of the Health Informatics Institute at
University of South Florida's Morsani College of Medicine and a principal investigator of the TEDDY and TrialNet type 1 diabetes studies.
RESEARCH AWARDS TO PROFESSOR MIKAEL KNIP
January 2017: TRIGR Study's Principal Investigator, Professor Mikael Knip, was awarded the 2017 Matti Äyräpää Prize by the Finnish
Medical Society Duodecim. The Matti Äyräpää Prize, which is granted annually, is the most meritorious medical prize in Finland for
successful research. As of 2017, the prize has been awarded only 49 times.
February 2011: Prof. Knip was awarded the 2010 Nordic Johnny Ludvigsson Research Prize for Excellent Research in Childhood and Adolescent Diabetes by the Swedish Child Diabetes
Foundation (Barndiabetesfonden) for his long-lasting and successful research on childhood diabetes. Prof. Knip delivered a prize lecture at a ceremony in Linköping held in
2011 and received a cheque (300,000 Swedish Crowns, approx. 32,000 euros) presented by Princess Victoria of Sweden.
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